(3+2) Dipolar cycloaddition of 1-pyrroline 1-oxide with 2-aryl-3-butenoates. Application to prepare bicyclic heterocyclic compounds.
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چکیده
منابع مشابه
Kinetics of the [4+2] cycloaddition of cyclopentadiene with (E)-2-aryl-1-cyano-1-nitroethenes
ABSTRACT The electrophilicity of (E)-2-aryl-1-cyano-1-nitroethenes is not sufficient to induce a zwitterionic course of their [4+2] cycloaddition to cyclopentadiene. The one-step mechanism of these reactions is indicated by the activation parameters, and the substituent and solvent effects on the reaction. GRAPHICAL ABSTRACT
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The synthesis of 6- methyl- 2- phenyl- 7H- oxazolo [3,2-b] 1,2,4-Triazine- 7-one (6, R=Ph) and its 2-P- bromophenyl analogue to the two members of a new heterocyclic system is described
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The dual diene/1,3-dipolar character of 1-H-imidazole 3-oxide, HIO 1, allows this compound toparticipate in a competitive Diels-Alder (DA)/1,3-dipolar cycloaddition (13DC) reaction toward C=Sdouble bond of the electro-deficient sulfonyl methane SFM 2. The B3LYP/6-311++G(d,p) calculatedrelative Gibbs free energies indicate that among the studied 13DC and DA reactions, former iscompletely preferr...
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Aldehyde phenyl hydrazones 2a-i undergo oxidative dehydrogenation with Chloramine-T to give nitrile imines, which are trapped in situ by ethyl oleate 1 to afford 8-(5-Aryl-4-octyl-2-phenyl-3,4-dihydro-2Hpyrazol-3-yl)-octanoic acid ethyl esters 3a-i in good yield. The structures of the cycloadducts were confirmed by spectral studies and elemental analysis.
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1985
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.33.351